Szopiński M., Sitko K., Rusinowski S., Zieleźnik-Rusinowska P., Corso M., Rostański A., Rojek-Jelonek M., Verbruggen N. and Małkowski E. Different strategies of Cd tolerance and accumulation in Arabidopsis halleri and Arabidopsis arenosa. Plant, Cell & Environment, in press.


Szopiński M., Sitko K., Gieroń Z., Rusinowski S., Corso M., Hermans C., Verbruggen N. and Małkowski E. Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes. Frontiers in Plant Science, doi: 10.3389/fpls.2019.00748.


Koch M., Busse M., Naumann M., Jákli B., Smit I., Cakmak I., Hermans C., Pawelzik E. Differential effects of varied potassium and magnesium nutrition on production and partitioning of photoassimilates in potato plants. Physiologia plantarum (in press).

Ahmadi H., Corso M., Weber M., Verbruggen N*. and Clemens S*. CAX1 suppresses Cd-induced generation of reactive oxygen species in Arabidopsis halleriPlant, Cell & Environment, 41, 2435-2448 (*co-last authors).

Lange B., Delhaye G., Boisson S., Verbruggen N., Meerts P., Faucon M.-P. Variation in copper and cobalt tolerance and accumulation among six populations of the facultative metallophyte Anisopappus chinensis (Asteraceae). Environmental and Experimental Botany 153, 1-9.

Corso M., Doccula F.G., de Melo J.R.F., Costa A., Verbruggen N. Endoplasmic reticulum-localized CCX2 is required for osmotolerance by regulating ER and cytosolic Ca2+ dynamics in Arabidopsis. PNAS, 115, 3966-3971.

Ilunga Kabeya F., Pongrac P., Lange B., Faucon M.-P., Van Elteren J., Sala M., Selih V.S. Vanden Eeckhoudt E., Verbruggen N. Tolerance and accumulation of cobalt in three species of Haumaniastrum and the influence of copper. Environmental and Experimental Botany 149, 27-33.

Corso M., Schvartzman M.S., Guzzo F., Souard F., Malkowski E., Hanikenne M., Verbruggen N. Contrasting cadmium resistance strategies in two metallicolous populations of Arabidopsis halleri. New Phytologist 218, 283-297.

Schvartzman M.S., Corso M., Fataftah N., Scheepers M., Nouet C., Bosman B., Carnol M., Motte P., Verbruggen N., Hanikenne M. Adaptation to high Zinc depends on distinct mechanisms in metallicolous populations of Arabidopsis halleri. New Phytologist 218, 269-282.


De Caluwé J., Fernandes de Melo J.R., Tosenberger A., Hermans C., Verbruggen N., Leloup J.-C. and Gonze D. Modeling the photoperiodic entrainment of the plant circadian clock. Journal of Theorical Biology 420, 220-231.

Juraniec M., Hermans C., Salis P., Geelen D. and Verbruggen N. Impact of post-flowering nitrate availability on nitrogen remobilization in hydroponically grown durum wheat. Journal of Plant Nutrition and Soil Science 180, 273-278.

Boisson S., Faucon M.-P., Le Stradic S., Lange B., Verbruggen N., Garin O., Tshomba Wetshy A., Séleck M., Masengo Kalengo W., Ngoy Shutcha M. and Mahy G. Specialized edaphic niches of  threatened copper endemic plant species in the D.R. Congo: implications for ex situ conservation. Plant and Soil 413, 261-273.

Lange B., van der Ent A., Baker A.J.M., Echevarria G., Mahy G., Malaisse F., Meerts P., Pourret O., Verbruggen N*. and Faucon M.-P*. Copper and cobalt accumulation in plants: a critical assessment of the current status of knowledge. New Phytologist 213, 537-551. (* co-last authors)


Meyer C.-L., Pauwels M., Briset L., Godé C., Salis P., Bourceaux A., Souleman D., Frérot H. and Verbruggen N. Potential preadaptation to anthropogenic pollution: evidence from a common quantitative trait locus for zinc and cadmium tolerance in metallicolous and nonmetallicolous accessions of Arabidopsis halleri. New Phytologist 212, 934-943.

Baliardini C., Corso M. and Verbruggen N. Transcriptomic analysis supports the role of CATION EXCHANGER 1 in cellular homeostasis and oxidative stress limitation during cadmium stress. Plant Signaling & Behavior 11, e1183861.

De Gernier H., De Pessemier J., Xu J., Cristescu S.M., Van Der Straeten D., Verbruggen N. and Hermans C. A comparative study of ethylene emanation upon nitrogen deficiency in natural accessions of Arabidopsis thaliana. Frontiers in Plant Science 7, 70.

De Caluwé J., Xiao Q., Hermans C., Verbruggen N., Leloup J.-C. and Gonze D. A compact model for the complex plant circadian clock. Frontiers in Plant Science 7, 74.

Juraniec M., Heyman J., Schubert V., Salis P., De Veylder L. and Verbruggen N. Arabidopsis CMR1/PANS1 is essential for growth adaptation to stress and required for mitotic onset control. New Phytologist 209, 177-191.


Xiao Q., De Gernier H., Kupcsik L., De Pessemier J., Dittert K., Fladung K., Verbruggen N. and Hermans C. Natural genetic variation of Arabidopsis thaliana root morphological response to magnesium supply. Crops & Pasture Science 66(12), 1249-1258.

Baliardini C., Meyer C.-L., Salis P., Saumitou-Laprade P. and Verbruggen N. CAX1 co-segregates with Cd tolerance in the metal hyperaccumulator Arabidopsis halleri and plays a role in limiting oxidative stress in Arabidopsis. Plant Physiology 169, 549-559.

Meyer C.-L., Juraniec M., Huguet S., Chaves-Rodriguez E., Salis P., Isaure M.-P., Goormaghtigh E. and Verbruggen N. Intra-specific variability of cadmium tolerance, accumulation and Cd-induced cell wall modifications in the metal hyperaccumulator Arabidopsis halleri. Journal of Experimental Botany 66(11), 3215-3227.

Isaure M.-P., Huguet S., Meyer C.-L., Castillo-Michel H., Testemale G., Vantelon D., Saumitou-Laprade P., Verbruggen N*. and Sarret G*. Evidence of various mechanisms of Cd sequestration in the hyperaccumulator Arabidopsis halleri, the non accumulator Arabidopsis lyrata and their progenies by combined synchrotron-based techniques. Journal of Experimental Botany 66(11), 3201-3214. (*co-last authors)


Juraniec M., Lequeux H., Hermans C., Willems G., Nordborg M., Schneeberger K., Salis P., Vromant M., Lutts S. and Verbruggen N. Towards the discovery of novel genetic component involved in stress resistance in Arabidopsis thaliana. New Phytologist 201(3), 810-824.


Clemens S., Aarts M.G.M., Thomine S. and Verbruggen N. Plant science : the key to preventing slow cadmium poisoning. Trends in Plant Science 18(2), 92-99.

Cristescu S.M., Mandon J., Arslanov D., De Pessemier J., Hermans C. and Harren F.J.M. Current methods for detecting ethylene in plants. Annals of Botany 111(3), 347-360.

De Pessemier J., Chardon F., Juraniec M., Delaplace P. and Hermans C. Natural variation of the root morphological response to nitrate supply in Arabidopsis thaliana. Mechanisms of Development 130(1), 45-53.

Verbruggen N. and Hermans C. Root responses to trace metallic elements in Plant Roots: The Hidden Half, 4th edition. Editors: Eshel A. and Beeckman T., CRC Press. ISBN 978-1-4398-4648-3.

Hermans C., Chen J. and Verbruggen N. Magnesium in plants. In : Encyclopedia of metalloproteins. Editors: Kreitsinger R., Permyakov E., and Uversky V.N., Springer Eds. ISBN 978-1-4614-1532-9.

Verbruggen N. and Hermans C. Physiological and molecular responses to magnesium nutritional imbalance in plants. Plant and Soil 368, 87-99.

Hermans C., Conn S., Chen J., Qiying X. and Verbruggen N. An update on magnesium homeostasis mechanisms in plants. Metallomics 5(9), 1170-1183.

Verbruggen N., Juraniec M., Baliardini C. and Meyer C.-L. Tolerance to cadmium in plants: the special case of hyperaccumulators. BioMetals 26(4), 633-638.

Verbruggen N., Hanikenne M., and Clemens S. A more complete picture of metal hyperaccumulation through next-generation sequencing technologies. Frontiers in Plant Science 4, 388.


Craciun A., Meyer C.-L., Chen J., Roosens N., De Groodt R., Hilson P. and Verbruggen N. Variation in HMA4 gene copy number and expression among Noccaea caerulescens populations presenting contrasted levels of Cd tolerance and accumulation. Journal of Experimental Botany 63(11), 4179-4189.

Faucon M.-P., Chipeng F., Verbruggen N., Mahy G., Colinet G., Shutcha M. and Meerts P. Copper tolerance and accumulation in two cuprophytes of South Central Africa: Crepidorhopalon perennis and C. tenuis (Scrophulariaceae). Environmental and Experimental Botany 84, 11-16.

Baxter I., Hermans C., Lahner B., Yabukova E., Tikhonova M., Verbruggen N., Chao D.-Y. and Salt D.E. Biodiversity of mineral nutrient and trace element accumulation in Arabidopsis thalianaPLoS ONE 7(4), e35121.

Rubio Fernandez L., Vandenbussche G., Roosens N., Govaerts C., Goormaghtigh E. and Verbruggen N. Metal binding properties and structure of a type III metallothionein from the metal hyperaccumulator plant Thlaspi caerulescens. Biochimica et Biophysica Acta 1824(9), 1016-1023.

Meyer C.-L. and Verbruggen N. Use of the model species Arabidopsis halleri towards phytoextraction of cadmium polluted soils. New Biotechnology 30(1), 9-14.


Ortega-Villasante C., Sobrino-Plata J., Carpena-Ruiz R.O., Verbruggen N., Escobar C. and Hernandez L.E. Oxidative stress induced by Cadmium in Transgenic Nicotiana tabacum over-expressing a plastidial Mn-superoxide dismutase. Functional Plant Science and Biotechnology 5(Special Issue 2), 62-67.

Meyer C-L., Peisker D., Courbot M., Craciun A., Cazale A-C., Desgain D., Schat H., Clemens S. and Verbruggen N. Isolation and characterization of Arabidopsis halleri and Thlaspi caerulescens phytochelatin synthases. Planta 234(1), 83-95.

Ruytinx J., Craciun A., Verstraelen K., Vangronsveld J., Colpaert J. and Verbruggen N. Transcriptome analysis by cDNA-AFLP on Suillus luteus Cd-tolerant and Cd-sensitive isolates. Mycorrhiza 21, 145-154.

Hermans C., Porco S., Vandenbussche F., Gille S., De Pessemier J., Van Der Straeten D., Verbruggen N. and Bush D.R. Dissecting the role of CTL1 in nitrate-dependent changes in root architecture. Plant Physiology 157, 1313-1326.

Hermans C., Chen J., Coppens F., Inzé D. and Verbruggen N. Low magnesium status in plants enhances tolerance to cadmium exposure. New Phytologist 192, 428-436.


Chipeng F., Hermans C., Colinet G., Faucon M-P., Ngongo Luhembwe M., Meerts P., Verbruggen N. Copper tolerance in the cuprophyte Haumaniastrum katangense. Plant and Soil 328, 235-244.

Hermans C., Vuylsteke M., Coppens F., Craciun A., Inzé D. and Verbruggen N. Early transcriptomic changes induced by magnesium deficiency in Arabidopsis thaliana reveal the alteration of circadian clock gene expression in roots and the triggering of abscisic acid-responsive genes. New Phytologist 187, 119-131.

Hermans C., Vuylsteke M., Coppens F., Cristescu S., Harren F., Inzé D. and Verbruggen N. Systems analysis of the responses to long-term magnesium deficiency and restoration in Arabidopsis thaliana.New Phytologist 187, 132-144.

Hermans C., Porco S., Verbruggen N. and Bush D.R. Chitinase-like protein CTL1 plays a role in altering root system architecture in response to multiple environmental conditions. Plant Physiology 152, 904-917.

Cubaka Kabagale A., Cornu B., van Vliet F., Meyer C.-L., Mergeay M.,  Lumbu Simbi J.-B., Droogmans L., Vander Wauven C. and Verbruggen N. Diversity of endophytic bacteria from the cuprophytes Haumaniastrum katangense and Crepidorhopalon tenuis. Plant & Soil 334, 461-474.

Frérot H, Faucon M-P, Willems G, Godé C, Courseaux A, Darracq A, Verbruggen N, Saumitou-Laprade P. Genetic architecture of zinc hyperaccumulation in Arabidopsis halleri: the essential role of QTL x environment interactions. New Phytologist 187(2), 355-367.

Lequeux H., Hermans C., Lutts S. and Verbruggen N. Response to copper excess in Arabidopsis thaliana: impact on the root system architecture, hormone distribution, lignin accumulation and mineral profile. Plant Physiology and Biochemistry 48(8), 673-682.

Willems G, Frérot H, Gennen J, Salis P, Saumitou-Laprade P and Verbruggen N. Quantitative Trait Loci analysis of mineral element concentrations in an Arabidopsis halleri x Arabidopsis lyrata petraeaF2 progeny grown on cadmium contaminated soil. New Phytologist 187(2), 368-379.


Faucon M-P., Colinet G., Mahy G., Ngongo Luhembwe M., Verbruggen N. and Meerts. P. Soil influence on Cu and Co uptake and plant size in the cuprophytes Crepidorhopalon perennis and C tenuis(Scrophulariaceae) in SC Africa. Plant and Soil 317: 201-212.

Krznaric E., Verbruggen N., H.L. Wevers P., Carleer R., Vangronsveld J. and V. Colpaert J., Cd-tolerant Suillus luteus: A fungal insurance for pines exposed to Cd. Environmental Pollution 157: 1581-1588.

Verbruggen N., Hermans C. and Schat H. Molecular mechanisms of metal hyperaccumulation and tolerance in plants. New Phytologist 181: 759-776.

Verbruggen N. and Leduc D. Potential of plant genetic engineering for phytoremediation of toxic trace elements. In: Phytotechnologies solutions for sustainable land management, [Ed.Tomas Vanek], in Encyclopedia of Life Support Systems (EOLSS), Developed under the Auspices of the UNESCO, Eolss Publishers, Oxford ,UK, [http://www.eolss.net].

Verbruggen N., Hermans C. and Schat H.. Mechanisms to cope with arsenic or cadmium excess in plants.Current Opinion in Plant Biology 12: 364–372.


Hermans C. and Verbruggen N. Proline accumulation in plants: a review. Amino Acids 35(4): 753-759.

Hermans C. and Verbruggen N. Enhancement of magnesium content in plants by exploiting ionomics and transcriptomics. In Dietary Magnesium: New Research A.W. Yardley editor, Nova Science Publishers, Inc. ISBN 978-1-60692-109-8.


Willems G., D.B. Dräger, Courbot M., Godé C., Verbruggen N. and Saumitou-Laprade P. The Genetic Basis of Zinc Tolerance in the Metallophyte Arabidopsis halleri ssp. halleri (Brassicaceae): An Analysis of Quantitative Trait Loci. Genetics 176: 659-674.

Hermans C., Hammond J.P., Verbruggen N. and White P.J. Response to Andrews et al.: correlations and causality. Trends in Plant Science 12: 532-533.

Courbot M., Willems G., Motte P., Arvidsson S., Saumitou-Laprade P. and Verbruggen N. A major QTL for Cd tolerance in Arabidopsis halleri co-localizes with HMA4, a gene encoding a heavy metal ATPase. Plant Physiology 144: 1052-1065.

A.H. Muller L., Craciun A., Lambaerts M., Verbruggen N., Vangronsveld J. and Colpaert J.V. cDNA-AFLP reveals considerable variation in gene expression profiles between heavy metal tolerant and nontolerant Suillus luteus isolates. Mycorrhiza 17: 571-580.


Craciun A.R., Courbot M., Bourgis F., Salis P., Saumitou-Laprade P. and Verbruggen N. Comparative cDNA-AFLP analysis of Cd-tolerant and -sensitive genotypes derived from crosses between the Cd hyperaccumulator Arabidopsis halleri and Arabidopsis lyrata ssp. petraea. Journal of Experimental Botany 57: 2967-2983.

Hermans C., Hammond J.P., White P.J. and Verbruggen N. How do plants respond to nutrient shortage by biomass allocation ? Trends in Plant Science 11(12): 610-617.


Dechamps C., Roosens N.H., Hotte C. and Meerts P.  Growth and mineral element composition in two ecotypes of Thlaspi caerulescens on Cd contaminated soil. Plant and Soil 273: 327–335.

Hermans C., Bourgis F., Faucher M., Strasser R.J., Delrot S. and Verbruggen N. Magnesium deficiency in sugar beets alters sugar partitioning and phloem loading in young mature leaves. Planta 220: 541-549.

Hermans C. and Verbruggen N. Physiological characterisation of Mg deficiency in Arabidopsis thaliana. Journal of Experimental Botany 56: 2153-2161.

Roosens N.H., Bernard C., Leplae R. and Verbruggen N. Adaptative evolution of MT3 in the Cd/Zn hyperaccumulator Thlaspi caerulescens.  Zeitschrift fur Naturforschung 60c: 224-228.

Roosens N.H., Bernard C., Leplae R. and Verbruggen N. Variations in plant metallothioneins: the heavy metal hyperaccumulator, Thlaspi caerulescens as a study case. Planta 222: 716-729.

Bourgis F., C.Botha F., Srikrishnan M., N. Hiten F., J. Rigden D. and Verbruggen N. Characterization and functional investigation of an Arabidopsis DNA encoding a homologue to the d-PGMase superfamily Journal of Experimental Botany 56(414): 1129-1142.


Bernard C., Roosens N., Czernic P., Lebrun M. and Verbruggen N. A novel CPx-ATPase from the cadmium hyperaccumulator Thlaspi caerulescens. FEBS Letters 569: 140-148.

Hermans C., Johnson G.N., Strasser R.J. and Verbruggen N. Physiological characterization of magnesium deficiency in sugar beet: acclimation to low magnesium differentially affects photosystems I and II. Planta 220: 344-355.

Roosens N.H., Bernard C., Leplae R. and Verbruggen N. Evidence for copper homeostasis function of metallothionein (MT3) in the hyperaccumulator Thlaspi caerulescens. FEBS Letters 577: 9-16.


Bert V., Meerts P., Saumitou-Laprade P., Salis P., Gruber W. and Verbruggen N. Genetic basis of Cd tolerance and hyperaccumulation in Arabidopsis halleri. Plant and Soil 249: 9-18.

Roosens N., Verbruggen N., Meerts P., Ximanez De Emban J.A.C. and Smith A. Natural variation in cadmium hyperaccumulation and its relationships to metal hyperaccumulation for seven populations of Thlaspi caerulescens from western Europe. Plant Cell & Environment 26: 1657-1672.